[Influence of halidor on experimental bronchospasm]

Through local stimulation of various structures of medulla oblongata a centrogenic bronchial spasm was simulated in acute tests on cats. A peripheral bronchial spasm was reporduced by stimulating the peripheral length of the vagus. An experimental bronchial spasm caused by activation of reticular nuclei and of a single fascicular nucleus halidor suppressed with doses half as large as the ones needed to inhibit the peripheral spasm. An application of halidor to the ground of the fourth ventricle tended to immediately lessen the intensity of the bronchial spasm, this suggesting a central component in the action of the drug.