Related Experiment Video
Updated: Aug 5, 2026

Measuring Local Anaphylaxis in Mice
Published on: October 14, 2014
A case of idiopathic anaphylaxis associated with respiratory infections
N Mazur1, R Patterson, D Perlman
1Division of Allergy-Immunology, Northwestern University Medical School, Chicago, Illinois, USA.
Background:
Anaphylaxis is associated with IgE-mediated reactions to foods, drugs, and other allergens. Exercise-induced anaphylaxis and food plus exercise-induced anaphylaxis have been reported. Anaphylactoid reactions with no mechanisms determined have been described with radiographic contrast media. Idiopathic anaphylaxis by definition is anaphylaxis with no identifiable external allergen or stimulus. In our series of more than 350 patients with idiopathic anaphylaxis, extensive evaluation has failed to identify a cause for the anaphylaxis.
Objective:
To report a first case of idiopathic anaphylaxis associated with coryzal symptoms.
Methods:
A patient was evaluated for idiopathic anaphylaxis. Appropriate therapy was initiated.
Results:
The patient's anaphylactic episodes are related to the occurrence of coryzal symptoms but no clear IgE-mediated mechanism was identified.
Conclusion:
This is the first reported association of anaphylaxis with an inciting factor of infection.
More Related Videos
Related Concept Videos
Allergic Reactions
Allergic Drug Reactions
Asthma: Pathogenesis and Management
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Asthma-I: Introduction
Allergic Reactions: Anaphylaxis
Asthma I: Introduction

