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Pancreatic exocrine studies in intact animals: historic and current methods
E Niebergall-Roth1, S Teyssen, M V Singer
1Department of Medicine IV, (Gastroenterology), University Hospital of Heidelberg at Mannheim, Germany.
Laboratory Animal Science
|January 20, 1998
Summary
This review details historical and current methods for animal pancreatic exocrine studies. It focuses on surgical techniques for collecting pancreatic secretions in dogs and other species, discussing each method
Area of Science:
- Veterinary Medicine
- Animal Physiology
Background:
- Pancreatic exocrine function studies are crucial for understanding digestive physiology.
- Accurate methods for collecting pancreatic secretions in intact animals are essential for research.
Purpose of the Study:
- To review and compare historical and contemporary techniques for pancreatic exocrine studies in intact animals.
- To provide a comprehensive overview of surgical procedures for pancreatic secretion collection.
Main Methods:
- Detailed examination of surgical techniques including pancreatic fistulas, duodenal pouches, and duodenal fistulas.
- Review of methods applied to various animal models: dogs, rats, cats, pigs, rabbits, cattle, sheep, and horses.
Main Results:
- Analysis of the advantages and disadvantages of different surgical approaches.
- Discussion of the indications and limitations associated with each method for pancreatic secretion collection.
Conclusions:
- The choice of method depends on the specific research question and animal species.
- A thorough understanding of these techniques is vital for successful pancreatic exocrine research.