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[Apical hypertrophic cardiomyopathy with right ventricular involvement]
F M Albanesi Filho1, M B Castier, J D Diamant
1Hospital Universitário Pedro Ernesto-UERJ.
Arquivos Brasileiros De Cardiologia
|February 1, 1997
Summary
Right ventricular involvement in apical hypertrophic cardiomyopathy (HCMP) indicates a worse prognosis. This condition presents differently from left ventricular disease, often leading to severe diastolic restriction and poorer outcomes.
Area of Science:
- Cardiology
- Cardiovascular Diseases
- Genetics
Background:
- Apical hypertrophic cardiomyopathy (HCMP) is a genetic heart muscle disease.
- Left ventricular involvement typically shows a good clinical evolution.
- Right ventricular (RV) involvement in HCMP is less understood.
Observation:
- Three patients (2 women, 1 man, aged 19-44) with apical HCMP and RV involvement were studied.
- Patients presented with severe diastolic restriction, significant atrial enlargement, and symptoms distinct from isolated left ventricular disease.
- Two patients experienced atrial fibrillation, leading to fatal thromboembolism.
Findings:
- Right ventricular involvement in apical HCMP is associated with a significantly worse prognosis compared to isolated left ventricular disease.
- RV involvement in apical HCMP does not present typical electrocardiographic changes.
- Clinical presentation includes ventricular restriction and tricuspid regurgitation.
Implications:
- Early identification of RV involvement in apical HCMP is crucial for risk stratification.
- Understanding RV involvement may lead to improved therapeutic strategies for managing apical HCMP.
- This finding highlights the importance of comprehensive cardiac assessment in apical HCMP patients.