Related Experiment Videos
Helicobacter pylori infection in a child with gastric augmentation
1Department of Pediatric Surgery, Cerrahpaşa Medical Faculty, University of Istanbul, Turkey.
Insights
Helicobacter pylori (HP) infection was identified in a child with a gastric augmentation for bladder exstrophy. This highlights the need for HP screening in gastrocystoplasty patients to prevent complications.
Area of Science:
- Pediatric Surgery
- Gastroenterology
- Urology
Background:
- Bladder augmentation using gastric tissue (gastrocystoplasty) is a surgical procedure for complex bladder conditions.
- Helicobacter pylori (HP) is a common bacterial infection affecting the stomach.
- The potential for HP infection in gastric segments used for bladder reconstruction has not been previously documented.
Observation:
- A pediatric patient with bladder exstrophy, who had undergone gastrocystoplasty, presented with persistent urinary and gastric symptoms.
- Diagnostic tests revealed a positive result for HP infection and elevated plasma gastrin levels.
- Histopathological examination of a biopsy from the neobladder confirmed HP infection within the gastric tissue.
Findings:
- This case report is the first to describe Helicobacter pylori infection in a pediatric patient with a history of gastrocystoplasty.
- The findings suggest a potential link between HP colonization and symptoms in patients with gastric augmentation for bladder reconstruction.
Implications:
- Pediatric surgeons should consider screening for HP infection in patients who have undergone gastrocystoplasty.
- Early detection and treatment of HP infection may mitigate risks associated with colonization in reconstructed bladders.
- This underscores the importance of considering gastrointestinal pathogens in patients with complex urological reconstructions involving gastric tissue.
Abstract:
The existence of Helicobacter pylori (HP) infection in those children who had previous bladder augmentation with gastric patch has not been described before. In this report, a girl with bladder exstrophy, who previously underwent gastric augmentation is presented. She had multiple admissions to our unit with persisting urinary symptoms (perineal pain, dysuria, hematuria) and gastric symptoms as well. Enzyme-linked immunosorbent assay (ELISA) test results for HP infection were positive, and plasma gastrin level was high. The histopathologic examination of the biopsy specimen showed HP infection in the gastric part of the reconstructed neobladder. This report indicates that the pediatric surgeon should think about HP infection in gastrocystoplasty patients to eliminate the potential risks of HP colonization.