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Primary and secondary osteosarcoma of the face: a rare childhood malignancy
P Maes1, B Brichard, C Vermylen
1Department of Pediatric Hematology and Oncology, Cliniques Universitaires Saint-Luc, Catholic University of Brussels, Belgium.
Background:
Osteosarcoma of the head and neck, especially primary forms, remains a rare and highly malignant tumor.
Patients:
This report describes two patients who developed an osteosarcoma of the face more than ten years after treatment for bilateral retinoblastoma. We also report a third patient who presented with a primary osteosarcoma of the right superior maxilla which is one of the rarest tumors encountered in childhood oncology.
Conclusions:
The mainstay of therapy is surgical resection with negative margins. Careful, long-term follow-up of survivors of hereditary retinoblastoma is essential, especially for those given radiation therapy.