Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Angiogenesis and cancer]

A Bikfalvi1, S Javerzat, C Perollet

  • 1Laboratoire des facteurs de croissance et de la différenciation cellulaire, Université de Bordeaux I, Talence, France.

Bulletin Du Cancer
|January 22, 1998
PubMed
Summary

Tumor invasion relies on angiogenesis, the process of new blood vessel formation. This review explores the molecular mechanisms and factors controlling angiogenesis, and its therapeutic implications in cancer biology.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Risk factors for RNA integrity in fresh-frozen renal cancer samples from routine practice (UroCCR 9).

The French journal of urology·2026
Same author

The strange Microenvironment of Glioblastoma.

Revue neurologique·2023
Same author

A model of guided cell self-organization for rapid and spontaneous formation of functional vessels.

Science advances·2019
Same author

Ligand activation induces different conformational changes in CXCR3 receptor isoforms as evidenced by plasmon waveguide resonance (PWR).

Scientific reports·2017
Same author

INHIBITION OF ERN1 SIGNALING ENZYME AFFECTS HYPOXIC REGULATION OF THE EXPRESSION OF E2F8, EPAS1, HOXC6, ATF3, TBX3 AND FOXF1 GENES IN U87 GLIOMA CELLS.

Ukrainian biochemical journal·2015
Same author

[Significance of the results of surgery in treatment of pulmonary tuberculosis].

Schweizerische Zeitschrift fur Tuberkulose. Revue suisse de la tuberculose. Rivista svizzera della tubercolosi·2014

Area of Science:

  • Oncology
  • Molecular Biology
  • Biochemistry

Context:

  • Tumorigenesis and cancer progression are complex processes.
  • Angiogenesis, the formation of new blood vessels, is crucial for tumor growth, invasion, and metastasis.
  • While many angiogenic factors and inhibitors are known, the precise molecular mechanisms remain incompletely understood.

Purpose:

  • To review recent advancements in the field of angiogenesis.
  • To summarize current knowledge on the molecular mechanisms governing angiogenesis.
  • To discuss the factors that regulate this process and its implications in cancer.

Summary:

  • This review synthesizes recent findings on the molecular mechanisms of angiogenesis, a critical process in tumor invasion and dissemination.
  • It details the known factors that control angiogenesis and provides an overview of current understanding.
  • The review also touches upon the pharmacological modulation of angiogenesis and its therapeutic relevance in cancer biology.

Impact:

  • Provides a comprehensive overview of angiogenesis in cancer, aiding researchers and clinicians.
  • Highlights knowledge gaps in the molecular mechanisms of angiogenesis, guiding future research directions.
  • Discusses therapeutic strategies targeting angiogenesis for improved cancer treatment outcomes.

Related Experiment Videos