Related Experiment Videos
Hematopoietic changes in rats after inescapable and escapable shocks
S A Malacrida1, N A Teixeira, M L Queiroz
1Department of Pharmacology and Hemocentre, Faculty of Medical Sciences, State University of Campinas, SP, Brazil.
Immunopharmacology and Immunotoxicology
|January 22, 1998
Abstract:
Bone marrow cell responsiveness to hematopoietic growth factors was investigated in rats only confined or experiencing inescapable, escapable shocks or no electric shock. The results demonstrated a significant reduction in the number of granulocyte-macrophage precursors in the bone marrow of confined rats and of rats exposed to inescapable shocks. The reversibility of this mielossupressive response was seen in both groups and occurred first in the confined animals. No changes were observed in the group submitted to escapable shocks when compared to controls.