Testing to fulfill HACCP (Hazard Analysis Critical Control Points) requirements: principles and examples
Related Experiment Video
Updated: Oct 9, 2026

High Content Screening Analysis to Evaluate the Toxicological Effects of Harmful and Potentially Harmful Constituents (HPHC)
Published on: May 10, 2016
1Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis 95616, USA.
Insights
Accurate on-farm Hazard Analysis Critical Control Points (HACCP) monitoring needs validated tests for cows, milk, and environment. Current limitations hinder consistent achievement of HACCP program goals due to a lack of field-validated diagnostic tools.
Area of Science:
- Dairy Science
- Food Safety
- Veterinary Diagnostics
Background:
- Effective on-farm Hazard Analysis Critical Control Points (HACCP) monitoring requires reliable tests for cows, milk, and the dairy environment.
- Tests must be field-validated to establish limitations for appropriate screening and interpretation of results.
- High specificity is crucial for low-prevalence infections and residues to minimize false positives and industry costs.
Purpose of the Study:
- To highlight the need for cost-effective, accurate, and reproducible field-validated tests for HACCP monitoring in dairy farming.
- To emphasize the importance of understanding test limitations for effective screening strategies and result interpretation.
- To address the challenges posed by the current lack of validated tests for chemical and infectious agents in achieving HACCP program objectives.
Main Methods:
- Review of current requirements for on-farm HACCP monitoring tests.
- Analysis of the impact of test specificity and prevalence on screening strategies.
- Evaluation of the implications of test validation status on HACCP program efficacy.
Main Results:
- Cost-effective, accurate, and reproducible tests are essential for dairy HACCP monitoring.
- Field validation and understanding test limitations are critical for rational interpretation and screening.
- Low specificity can lead to excessive costs and false positives, particularly for low-prevalence agents.
Conclusions:
- The dairy industry requires field-validated tests for effective HACCP implementation.
- Absence of positive results does not guarantee freedom from agents without 100% sensitive testing of the entire herd.
- A lack of validated tests impedes the consistent achievement of HACCP program goals for ensuring food safety.
Abstract:
On-farm HACCP (hazard analysis critical control points) monitoring requires cost-effective, yet accurate and reproducible tests that can determine the status of cows, milk, and the dairy environment. Tests need to be field-validated, and their limitations need to be established so that appropriate screening strategies can be initiated and test results can be rationally interpreted. For infections and residues of low prevalence, tests or testing strategies that are highly specific help to minimize false-positive results and excessive costs to the dairy industry. The determination of the numbers of samples to be tested in HACCP monitoring programs depends on the specific purpose of the test and the likely prevalence of the agent or residue at the critical control point. The absence of positive samples from a herd test should not be interpreted as freedom from a particular agent or residue unless the entire herd has been tested with a test that is 100% sensitive. The current lack of field-validated tests for most of the chemical and infectious agents of concern makes it difficult to ensure that the stated goals of HACCP programs are consistently achieved.
Related Concept Videos
Quality Control
Quality control helps track data, visualize trends, and identify variations, making it easier to detect deviations that may affect the accuracy of an analysis. One way to do this is by generating a quality control chart, which...
Quality Assurance
Introduction to Statistical Process Control
Sources of Food Contamination
Good Manufacturing Practices
Hazard Analysis and Critical Control Points (HACCP)

