The use of combinatorial and automated synthesis in drug discovery

Antibodies for neoplastic disease : solid tumors.

Methods in molecular medicine·2011

Effect of divalent metal ions on the binding of tissue factor and activated factor VII.

Thrombosis research·1997

A new combination of protecting groups and links for encoded synthetic libraries suited for consecutive tests on the solid phase and in solution.

Molecular diversity·1996

A comparative study of the brain uptake and early kinetics of 99mTc-dl HM-PAO and other PnAO derivatives in baboons.

Nuklearmedizin. Nuclear medicine·1986

Dinitrophenyl-pepstatins as active-site-directed localization reagents for cathepsin D.

The Biochemical journal·1983

Bimane-labelled pepstatin, a fluorescent probe for the subcellular location of cathepsin D.

The Biochemical journal·1981

Ageing, health and medication consumption in a sample of academic employees at a Mexican university.

Proceedings of the Western Pharmacology Society·2012

Treatment with LA-419 prevents monocrotaline-induced pulmonary hypertension and lung injury in the rat.

Proceedings of the Western Pharmacology Society·2012

Valproic acid modulates brain plasticity through epigenetic chromatin remodeling in the blind rat: implications for human sight recovery.

Proceedings of the Western Pharmacology Society·2012

Calmodulin antagonists inhibit sea urchin sperm hyperpolarization necessary for directed movement toward the egg.

Proceedings of the Western Pharmacology Society·2012

Ganoderma lucidum reduces kainic acid-induced hippocampal neuronal damage via inflammatory cytokines and glial fibrillary acid protein expression.

Proceedings of the Western Pharmacology Society·2012

Effect of orlistat on lipid peroxidation, Na+, K+ ATPase, glutathione and serotonin in rat brain.

Proceedings of the Western Pharmacology Society·2012

Colchicine and Major Adverse Cardiovascular Events in Patients With Established Coronary or Cerebrovascular Atherosclerotic Disease: A Systematic Review and Meta-Analysis of Randomised Controlled Trials.

Cureus·2026

Drimane-type sesquiterpenoids from aspergillus keveioides under OSMAC strategy characterized by GNPS possess in vitro antitumor cytotoxicity: A combined approach of bioactivity assay and network pharmacology.

Fitoterapia·2026

Emerging arylcyclohexylamine new psychoactive substances: Comprehensive characterization and differentiation by NMR, GC-MS, LC-QTOF-MS and LC-MS/MS.

Forensic science international·2026

High-resolution LC-MS/MS-based phytochemical profiling and antioxidant and anti-inflammatory activities of fig (Ficus carica L.) fruits, leaves, and twigs.

Food chemistry·2026

Acetazolamide use in idiopathic intracranial hypertension: a real-world cohort study of side effects.

Expert review of neurotherapeutics·2026

Research Trends and Mechanistic Insights Into Natural Medicines for Alzheimer's Disease: A Bibliometric Analysis and Narrative Review.

Phytotherapy research : PTR·2026

Related Experiment Videos

The use of combinatorial and automated synthesis in drug discovery

Related Concept Videos

Antibodies for neoplastic disease : solid tumors.

Effect of divalent metal ions on the binding of tissue factor and activated factor VII.

A new combination of protecting groups and links for encoded synthetic libraries suited for consecutive tests on the solid phase and in solution.

A comparative study of the brain uptake and early kinetics of 99mTc-dl HM-PAO and other PnAO derivatives in baboons.

Dinitrophenyl-pepstatins as active-site-directed localization reagents for cathepsin D.

Bimane-labelled pepstatin, a fluorescent probe for the subcellular location of cathepsin D.

Ageing, health and medication consumption in a sample of academic employees at a Mexican university.

Treatment with LA-419 prevents monocrotaline-induced pulmonary hypertension and lung injury in the rat.

Valproic acid modulates brain plasticity through epigenetic chromatin remodeling in the blind rat: implications for human sight recovery.

Calmodulin antagonists inhibit sea urchin sperm hyperpolarization necessary for directed movement toward the egg.

Ganoderma lucidum reduces kainic acid-induced hippocampal neuronal damage via inflammatory cytokines and glial fibrillary acid protein expression.

Effect of orlistat on lipid peroxidation, Na+, K+ ATPase, glutathione and serotonin in rat brain.

Colchicine and Major Adverse Cardiovascular Events in Patients With Established Coronary or Cerebrovascular Atherosclerotic Disease: A Systematic Review and Meta-Analysis of Randomised Controlled Trials.

Drimane-type sesquiterpenoids from aspergillus keveioides under OSMAC strategy characterized by GNPS possess in vitro antitumor cytotoxicity: A combined approach of bioactivity assay and network pharmacology.

Emerging arylcyclohexylamine new psychoactive substances: Comprehensive characterization and differentiation by NMR, GC-MS, LC-QTOF-MS and LC-MS/MS.

High-resolution LC-MS/MS-based phytochemical profiling and antioxidant and anti-inflammatory activities of fig (Ficus carica L.) fruits, leaves, and twigs.

Acetazolamide use in idiopathic intracranial hypertension: a real-world cohort study of side effects.

Research Trends and Mechanistic Insights Into Natural Medicines for Alzheimer's Disease: A Bibliometric Analysis and Narrative Review.

Related Experiment Videos

The use of combinatorial and automated synthesis in drug discovery

Related Concept Videos

Related Articles