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[Rotavirus-associated gastroenteritis in adults]

H Nakajima1, K Muramoto, T Mikami

  • 1Department of Medicine, Kuroishi City Hospital.

Nihon Shokakibyo Gakkai Zasshi = the Japanese Journal of Gastro-Enterology
|January 22, 1998
PubMed
Summary

Human rotavirus causes gastroenteritis in adults, with 21% of diarrhea cases testing positive. This finding highlights the need to recognize rotavirus-associated gastroenteritis in adult populations.

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Area of Science:

  • Virology
  • Gastroenterology
  • Epidemiology

Context:

  • Adult diarrhea cases were studied over 12 months in 1996.
  • 109 adult patients with diarrhea were evaluated.
  • Human rotavirus was investigated as a potential cause.

Purpose:

  • To evaluate the prevalence of human rotavirus in adult diarrhea cases.
  • To characterize rotavirus-associated gastroenteritis in adults.
  • To determine clinical and epidemiological features.

Summary:

  • Rotavirus antigen was detected in 23% of stool samples using ELISA.
  • Rotavirus-associated gastroenteritis predominantly occurred in summer months (June-September).
  • Hospitalization was required for 74% of affected adults, with some showing inflammatory changes on colonoscopy and bloody diarrhea.

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Impact:

  • Suggests the need to consider rotavirus as a cause of gastroenteritis in adults.
  • Highlights potential seasonal trends and severity of adult rotavirus infections.
  • Informs clinical recognition and management of adult diarrhea.