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Related Experiment Videos

Acute retinal necrosis late in the second trimester

K Shiraki1, M Moriwaki, S Ataka

  • 1Department of Ophthalmology, Osaka City University Medical School, Japan. shirakik@msci.med.osaka-cu.ac.jp

American Journal of Ophthalmology
|January 23, 1998
PubMed
Summary

This study details treating acute retinal necrosis in a pregnant patient with combined acyclovir and interferon therapy, followed by surgery. The treatment improved vision and resulted in a healthy delivery, demonstrating successful management during pregnancy.

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Area of Science:

  • Ophthalmology
  • Maternal-Fetal Medicine
  • Infectious Diseases

Background:

  • Acute retinal necrosis (ARN) is a severe viral retinitis that can lead to vision loss.
  • Management of ARN during pregnancy presents unique challenges due to potential risks to the fetus.

Observation:

  • A 24-year-old pregnant patient at 23 weeks gestation was diagnosed with ARN.
  • Treatment initiated included intravenous acyclovir and interferon therapy, followed by pars plana vitrectomy.

Findings:

  • The patient's visual acuity improved to 20/40 in the affected eye.
  • The necrotizing retina showed gliosis within 3 weeks post-surgery.
  • A healthy infant was delivered at 39 weeks gestation without complications.

Implications:

Related Experiment Videos

  • Combination therapy of antiviral agents and surgical intervention can be effective for ARN during pregnancy.
  • This approach appears safe for fetal development, allowing for successful pregnancy continuation.
  • Further research may explore optimal timing and specific regimens for ARN management in pregnant patients.