Related Experiment Videos
Acute retinal necrosis late in the second trimester
K Shiraki1, M Moriwaki, S Ataka
1Department of Ophthalmology, Osaka City University Medical School, Japan. shirakik@msci.med.osaka-cu.ac.jp
American Journal of Ophthalmology
|January 23, 1998
Summary
This study details treating acute retinal necrosis in a pregnant patient with combined acyclovir and interferon therapy, followed by surgery. The treatment improved vision and resulted in a healthy delivery, demonstrating successful management during pregnancy.
Area of Science:
- Ophthalmology
- Maternal-Fetal Medicine
- Infectious Diseases
Background:
- Acute retinal necrosis (ARN) is a severe viral retinitis that can lead to vision loss.
- Management of ARN during pregnancy presents unique challenges due to potential risks to the fetus.
Observation:
- A 24-year-old pregnant patient at 23 weeks gestation was diagnosed with ARN.
- Treatment initiated included intravenous acyclovir and interferon therapy, followed by pars plana vitrectomy.
Findings:
- The patient's visual acuity improved to 20/40 in the affected eye.
- The necrotizing retina showed gliosis within 3 weeks post-surgery.
- A healthy infant was delivered at 39 weeks gestation without complications.
Implications:
- Combination therapy of antiviral agents and surgical intervention can be effective for ARN during pregnancy.
- This approach appears safe for fetal development, allowing for successful pregnancy continuation.
- Further research may explore optimal timing and specific regimens for ARN management in pregnant patients.