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Prolactin hypersecretion and short luteal phase defects

B Corenblum, N Pairaudeau, A B Shewchuk

Obstetrics and Gynecology

|April 1, 1976

Summary

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Short luteal phase defects, often linked to infertility, can be an early sign of amenorrhea-galactorrhea syndrome. Antiprolactin therapy can restore normal fertility and resolve galactorrhea.

Area of Science:

Reproductive Endocrinology
Gynecology

Background:

Short luteal phase defects are common in infertile or clomiphene-induced ovulating women.
Galactorrhea, or abnormal milk production, can coexist with luteal phase defects.

Observation:

Two cases illustrate the short luteal phase defect as an early sign of developing amenorrhea-galactorrhea syndrome.
This syndrome involves the cessation of menstruation and galactorrhea.

Findings:

The short luteal phase defect may share a common cause with galactorrhea.
Antiprolactin therapy was effective in treating the presented cases.

Implications:

Identifying short luteal phase defects may aid in early diagnosis of the amenorrhea-galactorrhea syndrome.

Related Experiment Videos

Antiprolactin treatment offers a potential therapeutic strategy for restoring fertility and resolving galactorrhea.