The analysis of saccadic eye movements from gap and overlap paradigms

This protocol describes the acquisition and evaluation of saccadic eye movement data for use in basic neuroscience research and clinical application. The experimental protocol requires the subject to make saccadic eye movements in response to visual stimuli presented, in random order, on consecutive trials. The gap and overlap paradigms are described together with the instruction to generate pro- or antisaccades. The protocol includes the description of saccade detection, the determination of the beginning, the end, the size, and the velocity of a saccade, the exact way of calculating the proportion of different kinds of trials, and the treatment of erratic or artifact trials. Relevant variables are defined. The results obtained from a large number (300) of subjects of different ages (8-65 years) are described and analysed with respect to their development with age. The protocol allows to test a subject's saccadic status in many different circumstances in particular with respect to diagnostic help in neurology, psychiatry and psychology.