Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Asthma: Pathogenesis and Management

Asthma: Pathogenesis and Management

Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.

Chronic Obstructive Pulmonary Disease-II: Pathophysiology

Chronic Obstructive Pulmonary Disease-II: Pathophysiology

Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation

Asthma-I: Introduction

Asthma-I: Introduction

Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...

Asthma-II: Pathophysiology and Classification

Asthma-II: Pathophysiology and Classification

Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:

Asthma I: Introduction

Asthma I: Introduction

Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...

Asthma III: Clinical Manifestations

Asthma III: Clinical Manifestations

Asthma presents with a characteristic pattern of episodic respiratory symptoms that reflect underlying airway inflammation, bronchoconstriction, and mucus hypersecretion. Although severity varies among individuals, certain clinical manifestations are considered hallmarks of the disorder and often guide diagnosis and assessment.Respiratory SymptomsA persistent cough is one of the most common early features of asthma. It is frequently dry and tends to worsen at night or in the early morning,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Assessing the impact of childhood pneumococcal vaccination on pneumonia mortality in Colombia: a 14-year analysis.

BMC public health·2025

Same author

Occupational asthma induced by fish exposure.

Occupational medicine (Oxford, England)·2023

Same author

Disease severity impairs sleep quality in allergic rhinitis (The SOMNIAAR study).

Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology·2012

Same author

[Risk factors for basal cell carcinoma: a study from the national dermatology center of Colombia].

Actas dermo-sifiliograficas·2011

Same author

Immediate allergic reaction due to neomycin.

Journal of investigational allergology & clinical immunology·2009

Same author

Efficacy of mitomycin C associated with direct conjunctival closure and sliding conjunctival graft for pterygium surgery.

The British journal of ophthalmology·2007

Search research articles

Related Experiment Video

Updated: May 3, 2026

Collection and Extraction of Occupational Air Samples for Analysis of Fungal DNA

Collection and Extraction of Occupational Air Samples for Analysis of Fungal DNA

Published on: May 2, 2018

Occupational asthma induced by garlic dust

B Añibarro¹, J L Fontela, F De La Hoz

¹Hospital Virgen de la Luz, Cuenca, Spain.

The Journal of Allergy and Clinical Immunology

|January 23, 1998

Summary

Occupational asthma caused by garlic allergy is rare but affects young individuals with pollen allergies. Sensitization to other Liliaceae family members, like onions, is common in these cases.

Area of Science:

Allergy and Immunology
Occupational Health
Food Science

Background:

Immunoglobulin E (IgE)-mediated diseases are rarely attributed to garlic dust.
Occupational asthma is a significant concern for individuals exposed to specific environmental triggers.

Purpose of the Study:

To investigate occupational asthma in garlic workers.
To identify specific allergens in garlic responsible for IgE-mediated sensitization.

Main Methods:

Skin prick tests and serum-specific IgE were performed for garlic and related foods.
Bronchial challenge tests with garlic powder were conducted.
Protein analysis using electrophoresis and immunoblotting identified specific garlic allergens.

Main Results:

More Related Videos

Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber

Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber

Published on: March 3, 2023

Author Spotlight: Efficacy of Auricular Pressure Bean Therapy in Reducing Wheezing Symptoms

Author Spotlight: Efficacy of Auricular Pressure Bean Therapy in Reducing Wheezing Symptoms

Published on: May 10, 2024

Related Experiment Videos

Last Updated: May 3, 2026

Collection and Extraction of Occupational Air Samples for Analysis of Fungal DNA

Collection and Extraction of Occupational Air Samples for Analysis of Fungal DNA

Published on: May 2, 2018

Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber

Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber

Published on: March 3, 2023

Author Spotlight: Efficacy of Auricular Pressure Bean Therapy in Reducing Wheezing Symptoms

Author Spotlight: Efficacy of Auricular Pressure Bean Therapy in Reducing Wheezing Symptoms

Published on: May 10, 2024

Seven out of 12 garlic workers demonstrated garlic sensitization via bronchial challenge.
Patients with garlic allergy were young, frequently had pollen allergies, and showed cross-reactivity with other Liliaceae.
A 54 kd protein in garlic extract was identified as a major allergen.

Conclusions:

Occupational allergy to garlic was confirmed in seven patients.
Garlic allergy is uncommon but linked to young age, pollen allergy, and Liliaceae family sensitization.
Structural similarities exist between allergens in garlic, onion, and certain pollens.