Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Nursing Assessment of the Genitourinary System II: Inspection and Palpation

Nursing Assessment of the Genitourinary System II: Inspection and Palpation

The nursing assessment of the genitourinary (GU) system involves a systematic inspection and palpation to identify abnormalities in the kidneys, bladder, and surrounding structures.InspectionMouth: Inspect for signs of kidney dysfunction, such as stomatitis (inflammation of the mouth) and ammonia breath, which may occur in advanced kidney disease due to the buildup of urea, breaking down into ammonia.Skin: Check for pallor, which could indicate anemia caused by kidney disease. Look for...

Hemodialysis I: Introduction

Hemodialysis I: Introduction

Hemodialysis (HD) is a medical treatment that artificially removes waste products, excess fluids, and toxins from the blood when the kidneys are no longer able to perform these functions effectively. In this process, blood is filtered through a semipermeable membrane, allowing for the selective removal of waste while preserving necessary components like blood cells and proteins. Hemodialysis is typically performed in patients with end-stage renal disease (ESRD) or severe kidney...

Kidney Transplant I: Introduction

Kidney Transplant I: Introduction

A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...

Kidney Transplant II: Surgical Procedure

Kidney Transplant II: Surgical Procedure

Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living donor...

Kidney Transplant III: Nursing Management

Kidney Transplant III: Nursing Management

Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...

Acute Kidney Injury II: Pathophysiology

Acute Kidney Injury II: Pathophysiology

Acute kidney injury (AKI) causes are categorized into three primary categories based on the location of the injury: prerenal, intrarenal (or intrinsic), and postrenal causes. This classification guides clinical management and illustrates how different pathways can impair kidney function.Etiology and Pathophysiology of Acute Kidney Injury1. Prerenal causesEtiology: Prerenal Acute Kidney Injury, the most common type, occurs when reduced blood flow to the kidneys decreases filtration capacity...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

The Association Between Partner Reactions to Chronic Pain and Pain-Related Outcomes: A Systematic Review.

European journal of pain (London, England)·2026

Same author

Characteristics associated with antenatally unidentified small-for-gestational-age fetuses: prospective cohort study nested within DESiGN randomized controlled trial.

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2022

Same author

Improving antenatal detection of small-for-gestational-age fetus: economic evaluation of Growth Assessment Protocol.

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2022

Same author

Surgical ablation of lingual tonsils in the treatment of obstructive sleep apnea.

European annals of otorhinolaryngology, head and neck diseases·2018

Same author

Associations between high ambient temperatures and heat waves with mental health outcomes: a systematic review.

Public health·2018

Same author

Human resources for maternity care: the present system in Brazil, Japan, North America, Western Europe and New Zealand.

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics·2018

Search research articles

Related Experiment Video

Updated: Jul 12, 2026

Evaluation of Biomaterials for Bladder Augmentation using Cystometric Analyses in Various Rodent Models

Evaluation of Biomaterials for Bladder Augmentation using Cystometric Analyses in Various Rodent Models

Published on: August 9, 2012

Bladder augmentation can be problematic with renal failure and transplantation

E J Alfrey¹, O Salvatierra, D C Tanney

¹Department of Surgery, Stanford University, California 94305, USA.

Pediatric Nephrology (Berlin, Germany)

|January 23, 1998

Summary

Urinary bladder augmentation (UBA) may worsen kidney function in patients with chronic renal failure (CRF) or those awaiting transplantation. UBA takedown before kidney transplant improved outcomes for some patients, suggesting caution with UBA in these populations.

More Related Videos

A Modified Surgical Technique for Kidney Transplantation in Mice

A Modified Surgical Technique for Kidney Transplantation in Mice

Published on: July 22, 2022

A Rat Orthotopic Renal Transplantation Model for Renal Allograft Rejection

A Rat Orthotopic Renal Transplantation Model for Renal Allograft Rejection

Published on: February 2, 2022

Related Experiment Videos

Last Updated: Jul 12, 2026

Evaluation of Biomaterials for Bladder Augmentation using Cystometric Analyses in Various Rodent Models

Evaluation of Biomaterials for Bladder Augmentation using Cystometric Analyses in Various Rodent Models

Published on: August 9, 2012

A Modified Surgical Technique for Kidney Transplantation in Mice

A Modified Surgical Technique for Kidney Transplantation in Mice

Published on: July 22, 2022

A Rat Orthotopic Renal Transplantation Model for Renal Allograft Rejection

A Rat Orthotopic Renal Transplantation Model for Renal Allograft Rejection

Published on: February 2, 2022

Area of Science:

Urology
Nephrology
Transplantation Surgery

Background:

Urinary bladder augmentation (UBA) is a surgical procedure to enlarge the bladder.
Its use in patients with chronic renal failure (CRF) or end-stage renal disease (ESRD) requires careful consideration due to potential complications.

Purpose of the Study:

To evaluate the outcomes of urinary bladder augmentation (UBA) in patients with pre-existing chronic renal failure (CRF) or end-stage renal disease (ESRD).
To assess the impact of UBA on renal function and transplantation success in this patient cohort.

Main Methods:

A retrospective study of ten consecutive patients who experienced UBA failure.
Analysis of complications, progression to ESRD, and outcomes after UBA takedown and/or renal transplantation.

Main Results:

Seven patients with moderate CRF developed hydroureteronephrosis, infections, and advanced to ESRD after UBA, with a mean time of 1.8 years.
UBA takedown in these seven patients preceded transplantation, with five achieving stable graft function.
Three patients undergoing UBA after reaching ESRD for transplantation experienced recurrent urosepsis post-transplant, leading to one death and one graft loss.

Conclusions:

Urinary bladder augmentation may not be advisable for patients with moderate CRF or those awaiting renal transplantation.
Takedown of UBA prior to kidney transplantation can lead to successful graft function in selected cases.
UBA in patients with ESRD awaiting transplantation is associated with significant post-transplant infectious complications.