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Considerations in optimizing radiation therapy for non-small cell lung cancer
J S Greenberger1, S Bahri, J Jett
1Department of Radiation Oncology, University of Pittsburgh Medical Center and University of Pittsburgh Cancer Institute, PA 15213, USA.
Chest
|January 23, 1998
Abstract:
Irradiation therapy for lung cancer is mostly restricted to conventional methods. To improve therapeutic ratio, we have combined a treatment planning and a gene therapy approach. Three-dimensional conformal radiotherapy is described as carried out by methods of gene therapy for radiation protection using the manganese-superoxide-dismutase transgene delivered by inhalation gene transfer. These methods may improve therapeutic outcomes in lung cancer.