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Related Experiment Videos

Does candiduria predict candidaemia?

A Chakrabarti1, T C Reddy, S Singhi

  • 1Department of Medical Microbiology, Postgraduate Institute of Medical Education & Research, Chandigarh.

The Indian Journal of Medical Research
|January 24, 1998
PubMed
Summary
This summary is machine-generated.

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Candiduria (yeast in urine) is not a reliable indicator for candidaemia (yeast in blood) in children. Non-albicans Candida species in urine are a better predictor than Candida albicans.

Area of Science:

  • Medical Microbiology
  • Pediatric Infectious Diseases
  • Clinical Diagnostics

Background:

  • Blood culture is the gold standard for diagnosing candidaemia.
  • Low sensitivity and challenges in pediatric blood collection necessitate alternative diagnostic methods.
  • Evaluating candiduria as a non-invasive marker for systemic candidosis is crucial.

Purpose of the Study:

  • To assess the reliability of candiduria as an indicator of candidaemia in children.
  • To compare the diagnostic performance of urine culture and microscopy against blood cultures.
  • To investigate the predictive value of different Candida species in urine for systemic infection.

Main Methods:

  • Prospective study involving 91 pediatric intensive care unit patients with suspected disseminated candidosis.

Related Experiment Videos

  • Simultaneous blood and suprapubic urine cultures were performed.
  • Urine microscopy was also utilized for yeast detection.

    • Main Results:

    • Candida was isolated from blood in 41.8% and urine in 50.5% of patients.
    • Urine culture showed 65.8% sensitivity and 60.4% specificity for predicting candidaemia.
    • Non-albicans Candida species in urine (59.5%) were better predictors of candidaemia than C. albicans (33.3%).

    Conclusions:

    • Candiduria is not a sufficiently reliable indicator for diagnosing candidaemia in pediatric patients.
    • Urine microscopy offers comparable, but still limited, diagnostic accuracy.
    • Identification of non-albicans Candida species in urine warrants closer attention for potential systemic candidosis.