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Microsporidial keratoconjunctivitis in a patient without human immunodeficiency virus infection
B E Silverstein1, E T Cunningham, T P Margolis
1Francis I. Proctor Foundation, University of California, San Francisco 94122-0944, USA.
Purpose:
To describe a case of microsporidial keratoconjunctivitis in a patient without human immunodeficiency virus (HIV) infection.
Methods:
Case report. An epithelial corneal scraping from a woman with chronic bilateral keratoconjunctivitis was evaluated by Giemsa stain.
Results:
Giemsa stain of an epithelial corneal scraping disclosed intracellular and extracellular spores characteristic of microsporidia. An HIV enzyme-linked immunosorbent assay (ELISA) test was negative. The signs and symptoms of the bilateral keratoconjunctivitis resolved after treatment with albendazole.
Conclusion:
Microsporidia may cause a chronic epithelial keratoconjunctivitis in the absence of HIV infection.