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Related Experiment Videos

Peripapillary changes in glaucoma

J T Wilensky, A E Kolker

    American Journal of Ophthalmology
    |March 1, 1976
    PubMed
    Summary
    This summary is machine-generated.

    Glaucoma patients showed similar halo degrees but significantly more peripapillary atrophy than normal eyes. Extensive atrophy correlated with advanced, long-term glaucoma disease.

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    Area of Science:

    • Ophthalmology
    • Glaucoma Research

    Background:

    • Peripapillary halo and atrophy are clinical signs observed in the eye.
    • Understanding their association with glaucoma is crucial for diagnosis and management.

    Purpose of the Study:

    • To evaluate and compare the prevalence and severity of peripapillary halo and atrophy in glaucomatous versus normal eyes.
    • To determine if these features correlate with glaucoma severity and duration.

    Main Methods:

    • Three independent observers graded peripapillary halo and atrophy from 35-mm color transparencies of 240 eyes.
    • Clinical status of patients was unknown to the observers during grading.

    Main Results:

    • The average degree of peripapillary halo was statistically identical between glaucomatous and normal eyes.

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  • Peripapillary atrophy was significantly more extensive in glaucomatous eyes (P < .01).
  • Severe atrophy (4+) was predominantly observed in eyes with advanced, long-standing glaucoma.
  • Conclusions:

    • While peripapillary halo degree does not differentiate glaucomatous from normal eyes, peripapillary atrophy is a significant indicator.
    • Increased peripapillary atrophy is associated with advanced and chronic glaucoma, suggesting its utility in disease assessment.