Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Molecular domestication of mobile elements

W J Miller1, J F McDonald, W Pinsker

  • 1Department of Genetics, University of Georgia, Athens 30602, USA.

Genetica
|January 1, 1997
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Acquired resistance of pancreatic cancer cells to cisplatin is multifactorial with cell context-dependent involvement of resistance genes.

Cancer gene therapy·2016
Same author

Evidence for the role of microRNA 374b in acquired cisplatin resistance in pancreatic cancer cells.

Cancer gene therapy·2016
Same author

Clinical selection criteria can predict futile intervention in patients referred for percutaneous endoscopic gastrostomy insertion.

Internal medicine journal·2015
Same author

MDH-polymorphism in Drosophila subobscura: I. Selection and hitch-hiking in laboratory populations.

TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·2013
Same author

Transposable elements: possible catalysts of organismic evolution.

Trends in ecology & evolution·2011
Same author

Transposable elements, gene silencing and macroevolution.

Trends in ecology & evolution·2011
Same journal

Genomic insights into marine-freshwater transition: evolutionary adaptations in freshwater Pusa seals.

Genetica·2026
Same journal

Morphological and COI-based identification of species of the Hawkmoth genus Theretra Hübner, 1819 (Lepidoptera: Sphingidae) from Himachal Pradesh, India.

Genetica·2026
Same journal

Advancing genetics and evolution: new Editors-in-Chief in Genetica.

Genetica·2026
Same journal

Origin and diversification of Altai osmans (Oreoleuciscus), Far Eastern phoxinin minnows (Rhynchocypris) and Far Eastern redfins (Tribolodon) of the Leuciscidae family (Actinopterygii): an example of evolutionary tempo variation?

Genetica·2026
Same journal

Chloroplast genome comparison, phylogeny, and molecular evolution of five endemic Potentilla (Rosaceae) species in Mongolia.

Genetica·2026
Same journal

Severe trauma and chronic stress: seeds and fruits of epigenetic sensitivity.

Genetica·2026
See all related articles

Transposable elements (TEs) drive genome evolution by creating mutations. Some TE-mediated changes are now integral host genome features, impacting adaptive evolution.

Area of Science:

  • Genomics
  • Evolutionary Biology
  • Molecular Biology

Background:

  • Transposable elements (TEs) are mobile genetic sequences found in nearly all organisms.
  • TEs were historically considered selfish genetic elements with no positive impact on host evolution.
  • Recent findings suggest TEs can contribute to host genome evolution and adaptation.

Purpose of the Study:

  • To investigate the evolutionary impact of transposable elements on host genomes.
  • To explore the role of P element related gene clusters in Drosophila speciation.
  • To understand the process of molecular domestication of TE-derived sequences.

Main Methods:

  • Comparative genomics analysis of P element related gene clusters in Drosophila species.
  • Bioinformatic analysis of cis-regulatory regions and protein-coding sequences.

Related Experiment Videos

  • Phylogenetic analysis to trace the evolutionary history of TE-host gene interactions.

    • Main Results:

    • Identified stationary P element related gene clusters in D. guanche, D. madeirensis, and D. subobscura.
    • Characterized cis-regulatory regions and coding exons within these clusters.
    • Demonstrated that TE insertions can provide novel regulatory elements and contribute to gene evolution.

    Conclusions:

    • Transposable elements play a significant role in shaping host genome evolution.
    • Molecular domestication of TE sequences can lead to the emergence of new host genes.
    • Drosophila P element clusters serve as a valuable model for studying TE-mediated genome evolution.