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Synthesis of some 2-benzoxazolinone derivatives and their analgesic properties
H Erdogan1, S Eriskon, R Demirdamar
1Hacettepe University, Faculty of Pharmacy, Department of Pharmaceutical Chemistry, Ankara, Turkey.
Bollettino Chimico Farmaceutico
|January 24, 1998
Abstract:
In this study, the synthesis and analgesic activities of some new 6-acyl-3-(4-substituted benzoylmethyl)-2-benzoxazolinone derivatives are reported. Their structures were confirmed by microanalysis, IR, and NMR spectral analysis. The obtained compounds were screened for their analgesic activities. Analgesic activity of these compounds was investigated by modified Koster Test. The 11 compounds synthesized showed good analgesic activities.