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Cyclosporine: update on pharmacology, analytical techniques and therapeutic monitoring
L Santori1, M Rastelli, B Arena
1Laboratorio di Analisi Cliniche e Microbiologia, Ospedale Civile, Piacenza.
Bollettino Chimico Farmaceutico
|January 24, 1998
Abstract:
The Authors relate about the current state of knowledge on Cyclosporin A metabolism, mechanism of action, toxic potential, necessity of therapeutic monitoring. The methods for measurement of Cyclosporin A and its metabolites and the study of their immunosuppressive activity are described. Their use for measurement of Cyclosporin G is discussed.