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Does pulmonary tuberculosis change with ageing?

M Rocha1, S Pereira, H Barros

  • 1Serviço de Pneumologia, Hospital Joaquim Urbano, Faculdade de Medicina do Porto, Portugal.

The International Journal of Tuberculosis and Lung Disease : the Official Journal of the International Union Against Tuberculosis and Lung Disease
|April 1, 1997
PubMed
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This study found no specific clinical, bacteriological, or radiological differences in pulmonary tuberculosis between young and elderly patients. The findings do not support age-related patterns in tuberculosis presentation.

Area of Science:

  • Pulmonary Medicine
  • Infectious Diseases
  • Geriatrics

Background:

  • Tuberculosis (TB) is increasingly a disease of the elderly in low-prevalence countries.
  • A hypothesis suggests the elderly may present with distinct clinical patterns of TB.

Purpose of the Study:

  • To compare clinical, bacteriological, and radiological features of pulmonary tuberculosis between young (<60 years) and elderly (≥60 years) populations.
  • To investigate potential age-related patterns in TB presentation in a high-incidence setting.

Main Methods:

  • Retrospective study of 337 consecutive pulmonary tuberculosis patients without confirmed HIV infection.
  • Comparison of clinical, bacteriological, and radiological features between two age groups: young adults and the elderly.

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Main Results:

  • Fewer elderly patients reported thoracic pain and fever prior to hospitalization compared to younger patients.
  • No significant differences in general health status or comorbidities at admission were observed between age groups.
  • Radiological lesions unrelated to current TB and a presumed TB diagnosis were more frequent in the elderly.

Conclusions:

  • This study did not identify specific clinical, bacteriological, or radiological features distinguishing pulmonary tuberculosis in elderly versus younger patients.
  • The findings do not support the hypothesis of distinct age-related patterns in the presentation of pulmonary tuberculosis.