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[Light sedation in children. Midazole as nasal drops is a good alternative]
1Barneavdelingen, Ullevål sykehus, Oslo.
Insights
Midazolam nasal drops effectively sedate pediatric patients for medical procedures, offering a safe and convenient option. This method achieved a 78% success rate with minimal complications in 125 children.
Area of Science:
- Pediatric Anesthesiology
- Pharmacology
Context:
- Pediatric procedures often cause pain and fear.
- Sedation is crucial for patient comfort and procedural success.
- Midazolam is a common sedative agent.
Purpose:
- To evaluate the efficacy and safety of midazolam administered as nasal drops for pediatric sedation.
- To assess the success rate and complication profile of this administration route.
Summary:
- 125 pediatric patients (63 boys, 62 girls) received midazolam via nasal drops for procedures like echocardiography, venous/lumbar puncture, and CT scans.
- The overall success rate for sedation was 78%.
- Minor complications occurred in four children (vomiting, rash, prolonged sedation without respiratory compromise).
Impact:
- Midazolam nasal drops provide a safe and convenient method for sedating children.
- This approach can improve patient comfort and facilitate necessary medical interventions in pediatric care.
Abstract:
Many of the procedures carried out on paediatric patients are both painful and frightening to the child. To increase the child's comfort and to promote good working conditions, it may be necessary and advisable to sedate the child. In this study, 125 children (63 boys and 62 girls) were sedated with midazolam. For most children (n = 110) the medication was administered as nose drops. The reasons for sedation were echocardiography (n = 51), venous or lumbar punction (n = 53) and computer tomography scan (n = 21). The overall success rate was 78%. Minor complications were registered in four children. Two children vomited and one child developed a facial rash. One child had prolonged sedation, but this did not affect its respiration. We conclude that midazolam given as nose drops is a safe and convenient way of sedating paediatric patients.