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The role of chromatin in HIV-1 transcriptional regulation
1Swiss Institute for Experimental Cancer Research (ISREC), Epalinges, Switzerland. jmirkovi@isrec.unil.ch
Immunobiology
|January 27, 1998
Abstract:
Regulation of transcription is a key feature of the HIV-1 life cycle. In recent years, various sequence elements and transcription factors have been shown to participate in HIV-1 transcription control. New evidence, however, has shown that chromatin organization plays a key role in the establishment of a transcriptionally regulated HIV-1 LTR. The present review discusses recent data obtained on reconstituted and genomic HIV-1 chromatin templates.