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I-123 uptake in nonfunctional struma ovarii
I Joja1, T Asakawa, A Mitsumori
1Department of Radiology, Okayama University Medical School, Japan.
Clinical Nuclear Medicine
|January 27, 1998
Summary
Preoperative diagnosis of nonfunctional struma ovarii was achieved using iodine-123 (I-123) scintigraphy. This imaging technique proved useful in identifying the pelvic mass, aiding in accurate diagnosis.
Area of Science:
- Gynecologic Oncology
- Nuclear Medicine
- Radiology
Background:
- Struma ovarii is a rare germ cell tumor composed of mature thyroid tissue.
- Nonfunctional struma ovarii can be challenging to diagnose preoperatively.
- Multimodality imaging including ultrasound, CT, and MRI is often used for characterization.
Observation:
- A case of nonfunctional struma ovarii presented as a multilobulated pelvic mass with both cystic and solid components.
- CT demonstrated cystic areas of slightly high density, while MRI showed varied signal intensities on T1- and T2-weighted images.
- Pelvic scintigraphy using iodine-123 sodium iodide (I-123 NaI) revealed uptake in the pelvic mass.
Findings:
- Histologic examination confirmed the presence of thyroid tissue consistent with struma ovarii, including a follicular adenoma component.
- I-123 scintigraphy demonstrated functional thyroid tissue within the ovarian mass.
- The combination of imaging modalities, particularly I-123 scintigraphy, facilitated a correct preoperative diagnosis.
Implications:
- Iodine-123 scintigraphy is a valuable tool for the preoperative diagnosis of nonfunctional struma ovarii.
- Accurate preoperative diagnosis can guide surgical planning and management.
- This case highlights the utility of nuclear medicine in diagnosing rare gynecologic neoplasms.