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Ductal carcinoma in situ
1Department of Radiology, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
Critical Reviews in Diagnostic Imaging
|January 27, 1998
Summary
Screening mammography has increased diagnoses of ductal carcinoma in situ (DCIS), often detected by calcifications. Histologic classification remains debated, impacting breast conservation treatment decisions for these asymptomatic cancers.
Area of Science:
- Oncology
- Radiology
- Pathology
Background:
- The incidence of ductal carcinoma in situ (DCIS) has risen significantly over the past 20 years.
- Increased diagnosis is attributed to widespread screening mammography detecting asymptomatic cancers, often presenting as calcifications.
Purpose of the Study:
- To review established and proposed histologic classification systems for DCIS.
- To discuss the role and ongoing debates surrounding breast conservation therapy for DCIS.
Main Methods:
- Literature review of histologic classification systems for DCIS.
- Analysis of treatment guidelines and controversies regarding breast conservation for DCIS.
Main Results:
- Histologic classification of DCIS is currently controversial with various systems proposed.
- Breast conservation is generally accepted for many DCIS lesions, but specific applications remain under discussion.
Conclusions:
- Standardized histologic classification of DCIS is needed.
- Further clarification on the optimal application of breast conservation therapy for DCIS is warranted.