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Related Experiment Videos

Dientamoeba fragilis masquerading as allergic colitis

C Cuffari1, L Oligny, E G Seidman

  • 1Department of Pediatrics, Hôpital Sainte-Justine, Université de Montréal, Canada.

Journal of Pediatric Gastroenterology and Nutrition
|January 27, 1998
PubMed
Summary

Dientamoeba fragilis, a rare cause of chronic diarrhea in children, should be considered in differential diagnoses. Early identification and treatment are crucial for managing symptoms like eosinophilic colitis.

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Area of Science:

  • Pediatric Gastroenterology
  • Infectious Diseases
  • Microbiology

Background:

  • Dientamoeba fragilis is an uncommon pathogen causing chronic infectious diarrhea and colitis in pediatric patients.
  • Recognizing D. fragilis requires awareness of its epidemiological risk factors and clinical presentations.

Observation:

  • A review of 11 pediatric cases revealed diverse symptoms including anorexia, vomiting, abdominal pain, and prolonged diarrhea.
  • Seven patients presented with peripheral eosinophilia, and one with a bovine protein allergy experienced recurrent gastrointestinal issues.
  • Colonoscopy confirmed D. fragilis as the cause of eosinophilic colitis in one patient.

Findings:

  • Metronidazole and iodoquinol were effective treatments for D. fragilis infection in the studied pediatric cohort.

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  • Travel history was noted in seven of the eleven pediatric patients diagnosed with D. fragilis.

    • Implications:

    • D. fragilis should be included in the differential diagnosis for pediatric chronic diarrhea and eosinophilic colitis.
    • Accurate laboratory identification methods are essential for diagnosing D. fragilis infections.