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[Development after respiratortreatment during the newborn period (author's transl)]
Insights
Seventeen infants with severe neonatal respiratory distress survived over 24 hours of intermittent positive-pressure ventilation (IPPV). Most survivors were normal, but 17% had developmental or neurological defects, often linked to premature birth.
Area of Science:
- Neonatal Medicine
- Pediatric Neurology
Context:
- Neonatal respiratory distress is a critical condition requiring immediate intervention.
- Intermittent positive-pressure ventilation (IPPV) is a life-saving respiratory support method for neonates.
Purpose:
- To assess the long-term physical and neurological outcomes of infants surviving severe neonatal respiratory distress treated with IPPV.
Summary:
- 17 infants with severe neonatal respiratory distress received IPPV for over 24 hours and were followed into their second year.
- 11 survivors (65%) were physically and neurologically normal.
- 3 survivors (18%) had developmental delays, 2 (12%) had neurological defects (hemiplegia, diplegia) correlated with low gestational age, and 1 (6%) had severe defects.
Impact:
- This study highlights the potential for good neurodevelopmental outcomes in survivors of severe neonatal respiratory distress treated with IPPV.
- It identifies prematurity as a risk factor for neurological defects in this population.
- Findings underscore the importance of long-term follow-up for neonates requiring intensive respiratory support.
Abstract:
There were 17 survivors of severe neonatal respiratory distress treated with IPPV for more than 24 hours (36-520 hrs, mean duration of IPPV 6 days) followed into the second year of life. 11 of these young children were physically and neurologically normal. 3 were developmentally retarded (3 months or more), 2 had neurological defects without mental subnormality. These defects (Hemiplegia and Diplegia) were correlated with low gestational ages (32 and 33 weeks respectively) 1 child was severely defective. This one was treated because of apnea caused by seizures in postmaturity syndrome (44 weeks gestation). The overall incidence of defects was 3/17 (= 17%).