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Related Experiment Videos

Orbital plasmacytoma in a cat

D A Ward1, M F McEntee, D L Weddle

  • 1College of Veterinary Medicine, University of Tennessee, Knoxville 37901-1071, USA.

The Journal of Small Animal Practice
|January 28, 1998
PubMed
Summary
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A hyperviscosity syndrome in an Abyssinian cat, caused by elevated proteins and monoclonal gammopathy, led to organ damage. Postmortem examination revealed an extramedullary plasmacytoma as the underlying cause.

Area of Science:

  • Veterinary Medicine
  • Oncology
  • Hematology

Background:

  • Hyperviscosity syndrome can manifest in cats due to conditions causing elevated plasma proteins.
  • Monoclonal gammopathy indicates an overproduction of a single type of immunoglobulin, often associated with plasma cell disorders.

Observation:

  • An Abyssinian cat presented with epistaxis, melaena, and retinal vascular changes.
  • Markedly elevated plasma protein levels and monoclonal gammopathy were noted on serum protein electrophoresis.

Findings:

  • The clinical signs were initially attributed to hyperviscosity syndrome.
  • The cat showed a temporary response to fluid therapy but relapsed.
  • Unilateral exophthalmia developed, leading to euthanasia.

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Implications:

  • Extramedullary plasmacytoma, an uncommon plasma cell tumor, can cause hyperviscosity syndrome and diverse clinical signs.
  • This case highlights the importance of thorough postmortem examination for diagnosing rare neoplastic conditions.
  • Understanding the link between plasmacytomas and hyperviscosity is crucial for feline oncology and internal medicine.