[The apolipoprotein AII gene is not a risk factor for development ischemic heart disease in the Moscow population]

Polymorphism of microsatellite (CA)n repeat in the second intron of the apolipoprotein AH gene--one of the major structural proteins of high-density lipoproteins--was performed in male coronary heart disease (CHD) patients and in a random sample of men from the Moscow population. No association between the polymorphism and the development of CHD was revealed. Therefore, apolipoprotein AII gene is not a factor of genetic risk of the development of atherosclerosis in the population studied.