Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Therapeutic plasma exchange 1996]

U Weber1, W Riegel, H Köhler

  • 1Medizinische Klinik IV, Universitätskliniken Homburg/Saar.

Medizinische Klinik (Munich, Germany : 1983)
|January 31, 1998
PubMed
Summary

Therapeutic plasma exchange (TPE) removes harmful substances from blood. It is currently approved for specific autoimmune and hematologic conditions like TTP/HUS and myasthenia gravis.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cryptic T cell epitopes in polymorphic immunoglobulin regions: evidence for positive repertoire selection during fetal development.

European journal of immunology·1992
Same author

Two major groups of neutralizing anti-gp120 antibodies exist in HIV-infected individuals. Evidence for epitope diversity around the CD4 attachment site.

Journal of immunology (Baltimore, Md. : 1950)·1992
Same author

Human monoclonal and polyclonal anti-human immunodeficiency virus-1 antibodies share a common clonotypic specificity.

European journal of immunology·1992
Same author

[Baclofen intoxication in chronic hemodialysis and kidney transplantation].

Deutsche medizinische Wochenschrift (1946)·1992
Same author

Anti-idiotype monoclonal antibody elicits broadly neutralizing anti-gp120 antibodies in monkeys.

Proceedings of the National Academy of Sciences of the United States of America·1992
Same author

Synthetic peptides from a conserved region of gp120 induce broadly reactive anti-HIV responses.

Immunology·1992

Area of Science:

  • Clinical Medicine
  • Nephrology
  • Neurology
  • Hematology

Background:

  • Therapeutic plasma exchange (TPE) is an extracorporeal blood purification method.
  • TPE removes large molecular weight substances implicated in disease pathogenesis.
  • Its use has evolved since the late 1970s.

Purpose of the Study:

  • To outline the current accepted indications for Therapeutic Plasma Exchange.
  • To define specific diseases where TPE is a recognized treatment modality.

Main Methods:

  • Review of established medical literature and clinical guidelines.
  • Identification of diseases with proven benefit from TPE therapy.

Main Results:

  • Accepted indications for TPE are limited to specific, well-defined conditions.
  • These include anti-glomerular basement membrane disease, TTP/HUS, Guillain-Barré syndrome, hyperviscosity syndrome, and certain neuropathies.

Conclusions:

  • TPE is a valuable therapeutic option for a select group of serious medical conditions.
  • Its application is restricted to diseases where humoral factors are key pathogenic elements and TPE has demonstrated efficacy.

Related Experiment Videos