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Lymphocytic thyroiditis in beagle dogs in a breeding colony: findings of serum autoantibodies
1Institute of Histology and Embryology, 2nd Faculty of Medicine, Charles University, Praha, Czech Republic. Ludek.Vajner@lfmotol.cuni.cz
Three serum autoantibodies against antigens of the thyroid gland were detected by the indirect immunofluorescence in a Beagle dog breeding colony. The anti-thyroglobulin autoantibody was present in 10.0%, the anti-microsomal antigen autoantibody was present in 24.6%, and the anti-nuclear substance autoantibody in 10.8% of examined sera, respectively. Only the presence of anti-thyroglobulin autoantibodies could be correlated with histologic findings of the lymphocytic thyroiditis in the same colony.
Three serum autoantibodies against antigens of the thyroid gland were detected by the indirect immunofluorescence in a Beagle dog breeding colony. The anti-thyroglobulin autoantibody was present in 10.0%, the anti-microsomal antigen autoantibody was present in 24.6%, and the anti-nuclear substance autoantibody in 10.8% of examined sera, respectively. Only the presence of anti-thyroglobulin autoantibodies could be correlated with histologic findings of the lymphocytic thyroiditis in the same colony.