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Basilar membrane velocity noise

A L Nuttall1, M Guo, T Ren

  • 1Oregon Hearing Research Center (NRC04), Department of Otolaryngology Head and Neck Surgery, Oregon Health Sciences University, Portland 97201-3098, USA. nuttall@ohsu.edu

Hearing Research
|February 3, 1998
PubMed
Summary
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Basilar membrane (BM) noise reflects internal cochlear activity, not external sound. This internal noise amplitude and frequency correlate with normal cochlear sensitivity and frequency selectivity.

Area of Science:

  • Auditory Neuroscience
  • Bioacoustics
  • Otoacoustic Emissions

Background:

  • Basilar membrane (BM) noise is a low-level vibration present even in quiet conditions.
  • Understanding the origin and characteristics of BM noise is crucial for comprehending cochlear mechanics and function.

Purpose of the Study:

  • To investigate the origin and characteristics of basilar membrane (BM) noise in guinea pigs.
  • To determine whether BM noise originates from internal or external sources.
  • To assess the relationship between BM noise and cochlear sensitivity and frequency selectivity.

Main Methods:

  • Surgical exposure of guinea pig cochleas for direct BM visualization.
  • Measurement of BM velocity using laser interferometry.
  • Analysis of BM velocity noise spectra under various physiological and acoustic conditions, including electrical stimulation.

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Main Results:

  • BM noise exhibits a band-limited spectrum peaking at the best frequency of the measurement location.
  • BM noise amplitude is significantly reduced when cochlear sensitivity decreases.
  • External acoustic noise and middle ear blockage do not alter BM noise, while electrical stimulation of the crossed olivocochlear bundle depresses it.
  • BM noise characteristics mirror cochlear sensitivity and frequency selectivity.

Conclusions:

  • BM noise represents internal physiological processes rather than external acoustic stimuli.
  • The amplitude and frequency of BM noise are reliable indicators of normal cochlear sensitivity and frequency selectivity.
  • Potential sources of internal BM noise include remote mechanical vibrations or Brownian motion within the cochlea.