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Detection of Invasive Pulmonary Aspergillosis in Haematological Malignancy Patients by using Lateral-flow Technology
08:01

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Articular aspergillosis: two case reports and review of the literature

S Steinfeld1, P Durez, J P Hauzeur

  • 1Division of Rheumatology, Erasmus Hospital, University of Brussels, Belgium.

British Journal of Rheumatology
|February 4, 1998
PubMed

Insights

Two cases of knee septic arthritis caused by Aspergillus species were identified. Aspergillus recovery from synovial fluid indicates pathogenicity, especially in immunocompromised patients.

Area of Science:

  • Infectious Diseases
  • Mycology
  • Rheumatology

Background:

  • Septic arthritis is a serious joint infection.
  • Aspergillus species are fungi that can cause opportunistic infections.
  • Immunocompromised individuals are at higher risk for invasive fungal infections.

Observation:

  • Two distinct cases of knee septic arthritis due to Aspergillus were documented.
  • Case 1 involved Aspergillus terreus in a patient with liver cirrhosis.
  • Case 2 involved Aspergillus fumigatus following a vascular graft infection.

Findings:

  • Aspergillus species were identified as causative agents of septic arthritis.
  • Synovial fluid analysis is crucial for diagnosing Aspergillus septic arthritis.
  • The pathogenic potential of Aspergillus in joint infections is highlighted.

Implications:

  • Clinicians should consider Aspergillus in the differential diagnosis of septic arthritis, particularly in at-risk populations.
  • Prompt diagnosis and treatment are essential for favorable outcomes in Aspergillus septic arthritis.
  • Further research into the pathogenic mechanisms and treatment strategies for Aspergillus septic arthritis is warranted.

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