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Related Experiment Videos

Antipsychotic agents and bipolar disorder

M Tohen1, C A Zarate

  • 1Bipolar and Psychotic Disorders Program, McLean Hospital, Belmont, MA 02178, USA.

The Journal of Clinical Psychiatry
|February 4, 1998
PubMed
Summary

Antipsychotic agents are crucial for bipolar disorder treatment. This review covers their historical use and current role in acute and maintenance therapy, including newer atypical antipsychotics.

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Area of Science:

  • Psychiatry
  • Pharmacology

Background:

  • Antipsychotic agents are frequently prescribed for managing bipolar disorder.
  • Their therapeutic applications have evolved significantly over time.

Purpose of the Study:

  • To review the historical development and current utilization of antipsychotic agents in bipolar disorder treatment.
  • To highlight the role of both typical and atypical antipsychotics, including recent drug approvals.

Main Methods:

  • Literature review focusing on the evolution and application of antipsychotic drugs.
  • Analysis of neuroleptic drugs, atypical antipsychotics (risperidone, clozapine), and newer agents.

Main Results:

  • Antipsychotic agents have a well-established role in bipolar disorder management.
  • Atypical antipsychotics represent a significant advancement in treatment options.

Conclusions:

  • Antipsychotic medications are integral to both acute and long-term management of bipolar disorder.
  • The development of novel atypical antipsychotics continues to expand therapeutic possibilities.

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