Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Small-intestinal transplantation

O Goulet1, D Jan, N Brousse

  • 1Service de Gastroentérologie et Nutrition Pédiatriques, Université René Descartes, Hôpital Necker-Enfants Malades, Paris, France.

Bailliere'S Clinical Gastroenterology
|February 4, 1998
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Obsessive-compulsive disorder and depression in university students: serial mediation of (intrusive and deliberate) rumination and social anxiety.

BMC psychology·2026
Same author

Semantic inhibition impairment in college students with depressive states as evidenced by EEG and pupillometry during the hayling task.

Scientific reports·2024
Same author

"Modified tongue-in-groove": a new tip-plasty technique and comparison of its effect on correction of the nasolabial angle with the columellar strut technique.

The British journal of oral & maxillofacial surgery·2020
Same author

[Anatomic study of the submental artery relationships for submental flap raising].

Revue de stomatologie, de chirurgie maxillo-faciale et de chirurgie orale·2016
Same author

Determinants of vitamin D supplementation prescription in nursing homes: a survey among general practitioners.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2016
Same author

Gait speed or gait variability, which one to use as a marker of risk to develop Alzheimer disease? A pilot study.

Aging clinical and experimental research·2015
Same journal

Index.

Bailliere's clinical gastroenterology·2020
Same journal

Home enteral and parenteral nutrition in children.

Bailliere's clinical gastroenterology·1999
Same journal

Nutritional support in malnourished paediatric patients.

Bailliere's clinical gastroenterology·1999
Same journal

Cholestasis and end-stage liver disease.

Bailliere's clinical gastroenterology·1999
Same journal

Cystic fibrosis: nutritional consequences and management.

Bailliere's clinical gastroenterology·1999
Same journal

Pancreatic diseases (excluding cystic fibrosis).

Bailliere's clinical gastroenterology·1999
See all related articles

Intestinal transplantation offers a life-saving option for patients with intestinal failure, particularly when home parenteral nutrition (PN) is insufficient. Survival rates are improving, making it a viable therapeutic choice for select patients.

Area of Science:

  • Gastroenterology
  • Transplant Surgery
  • Clinical Nutrition

Background:

  • Parenteral nutrition (PN) advancements have improved intestinal failure management.
  • Intestinal transplantation is emerging as a critical therapeutic option for select patients.
  • Over 180 small-bowel grafts have been performed since 1985.

Purpose of the Study:

  • To review the outcomes and indications of intestinal transplantation.
  • To assess patient and graft survival rates based on different protocols.
  • To evaluate the role of intestinal transplantation in managing intestinal failure.

Main Methods:

  • Analysis of data from over 180 small-bowel grafts performed globally.
  • Review of patient demographics, indications, graft types, and survival rates.

Related Experiment Videos

  • Comparison of outcomes based on immunosuppression protocols (cyclosporine vs. FK506).

    • Main Results:

    • Short-bowel syndrome was the primary indication (64%), predominantly in patients under 20.
    • Two-year patient survival exceeded 51%, influenced by immunosuppression.
    • Functional grafts enabled gastrointestinal autonomy and improved nutritional status.

    Conclusions:

    • Intestinal transplantation is a viable option for patients with intestinal failure refractory to PN.
    • Careful consideration of risks versus benefits and quality of life is crucial for patient selection.
    • Isolated small-bowel transplantation is preferred, with combined liver-small bowel grafts reserved for severe liver disease.