Oligosaccharide beta-glucans with unusual linkages from Sarcina ventriculi
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Updated: Oct 30, 2026

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1Department of Chemistry, Michigan State University, East Lansing 48824, USA.
Abstract:
The structure of a family of unusual glucans from Sarcina ventriculi has been characterized by NMR spectroscopy, methylation analysis, and mass spectrometry. One is a trisaccharide containing a beta-(1-->3) and a beta-(1-->4)-linkage. The other is a hexasaccharide that is simply a 1,4-linkage dimer of the trisaccharide unit. This is the first report of beta-glucan biosynthesis in a Gram-positive organism. Their occurrence in these organisms supports an even more general link between their synthesis and the adaptability of bacteria.
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