An autopsy case of H.C.G. secreting intracranial teratoma

An autopsy case of intracranial malignant teratoma, in an 8 years old female, is presented in this report. Clinically, pregnancy test was positive and human chorionic gonadotropins of high titer were found in the urine but precocious puberty was not seen. The tumor was composed of differentiated teratomatous components and embryonal carcinoma with small foci of chorio-carcinoma. Embryonal carcinoma seemed to undergo trophoblastic differentiation. These histological findings have been discussed from the viewpoint of its histogenesis and differentiation.