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Updated: Aug 15, 2026

Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus
Published on: March 6, 2019
The rational clinical examination. Does this infant have pneumonia?
1Division of Community Pediatrics, The University of North Carolina at Chapel Hill, 27599-7225, USA. margolis@med.unc.edu
Insights
The clinical examination can accurately detect pneumonia in children. Absence of rapid breathing is the best sign for ruling out pneumonia, while signs of difficult breathing increase its likelihood.
Area of Science:
- Pediatrics
- Pulmonology
- Diagnostic Accuracy
Background:
- Acute lower respiratory tract illness is frequent in children presenting to primary care.
- Distinguishing viral from bacterial pneumonia is crucial for appropriate treatment.
- The accuracy of clinical examination findings in pediatric pneumonia requires thorough evaluation.
Purpose of the Study:
- To review the accuracy and precision of the clinical examination in diagnosing pneumonia in children.
- To identify key clinical signs indicative of pediatric pneumonia.
- To assess the reliability of clinical findings in primary care settings.
Main Methods:
- Systematic review of studies published between 1982 and 1995.
- Inclusion criteria involved studies on the clinical examination for pediatric pneumonia.
- Data extraction and quality assessment by two independent observers.
Main Results:
- Good observer agreement was found for most observable signs (e.g., accessory muscle use, color, attentiveness).
- Agreement was lower for auscultation findings (e.g., adventitious sounds).
- Absence of tachypnea is the strongest indicator for ruling out pneumonia; increased work of breathing suggests pneumonia.
Conclusions:
- Clinical examination is valuable for diagnosing pediatric pneumonia, with specific signs being more reliable than others.
- A negative clinical assessment (respiratory rate, auscultation, work of breathing) makes pneumonia unlikely.
- Further research is needed to evaluate the combined utility of clinical findings in diagnosing pediatric pneumonia.
Abstract:
Acute lower respiratory tract illness is common among children seen in primary care. We reviewed the accuracy and precision of the clinical examination in detecting pneumonia in children. Although most cases are viral, it is important to identify bacterial pneumonia to provide appropriate therapy. Studies were identified by searching MEDLINE from 1982 to 1995, reviewing reference lists, reviewing a published compendium of studies of the clinical examination, and consulting experts. Observer agreement is good for most signs on the clinical examination. Each study was reviewed by 2 observers and graded for methodologic quality. There is better agreement about signs that can be observed (eg, use of accessory muscles, color, attentiveness; kappa, 0.48-0.66) than signs that require auscultation of the chest (eg, adventitious sounds; kappa, 0.3). Measurements of the respiratory rate are enhanced by counting for 60 seconds. The best individual finding for ruling out pneumonia is the absence of tachypnea. Chest indrawing, and other signs of increased work of breathing, increases the likelihood of pneumonia. If all clinical signs (respiratory rate, auscultation, and work of breathing) are negative, the chest x-ray findings are unlikely to be positive. Studies are needed to assess the value of clinical findings when they are used together.
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