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Related Experiment Videos

Contraposed curve patterns in monozygotic twins

J A Ogden, W O Southwick

    Clinical Orthopaedics and Related Research
    |May 1, 1976
    PubMed
    Summary

    Monozygotic twins with Marfan syndrome showed opposite lumbar spine curves. The severity of spinal curvature correlated with other Marfan syndrome clinical signs.

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    Area of Science:

    • Genetics and Molecular Biology
    • Orthopedics
    • Clinical Medicine

    Background:

    • Marfan syndrome is a genetic disorder affecting connective tissue.
    • Skeletal manifestations, including scoliosis, are common in Marfan syndrome.
    • Discordance in clinical presentation among monozygotic twins can offer insights into disease variability.