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Updated: Aug 17, 2026

Chromosome Preparation From Cultured Cells
Published on: January 28, 2014
Chromosomal markers: signposts on the road to understanding neoplastic disease
1Department of Pathology, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA.
Abstract:
Classical cytogenetic studies have defined chromosomal attributes of tumors that are useful at present in the diagnosis, classification, and management of leukemic disorders, and in some solid tumors as well. Recent advances in molecular techniques now permit application of some forms of chromosomal analysis to studies in cytopathology. However, to fully understand the present and potential uses of these tumor markers, it is necessary to have some background and perspective on classical cytogenetics.
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