Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Axonal processes and neural plasticity. III. Competition for dendrites

T Elliott1, C I Howarth, N R Shadbolt

  • 1Department of Psychology, University of Nottingham, UK.

Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences
|February 6, 1998
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Survival and temporal change in the viability of <i>Ascaridia galli</i> eggs exposed to refrigeration or freezing temperatures in the presence of a cryoprotectant.

Journal of helminthology·2025
Same author

Translation of Prognostic and Pharmacodynamic Biomarkers from Trial to Non-trial Patients with Metastatic Castration-resistant Prostate Cancer Treated with Docetaxel.

Clinical oncology (Royal College of Radiologists (Great Britain))·2022
Same author

Viability and development of <i>Ascaridia galli</i> eggs recovered in artificial media followed by storage under different conditions.

Journal of helminthology·2020
Same author

Glycerin suppositories used prophylactically in premature infants (supp): A pilot randomized controlled trial.

Journal of neonatal-perinatal medicine·2020
Same author

Utility of Prognostic Markers in Second-line Treatment of Metastatic Urothelial Cancer.

Clinical oncology (Royal College of Radiologists (Great Britain))·2017
Same author

A national survey of current practices of preparation and management of radical prostate radiotherapy patients during treatment.

Radiography (London, England : 1995)·2017
Same journal

The microlandscapes of tree trunks: the effect of lichen and tree-level characteristics on arthropod communities.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences·2026
Same journal

Centimetre-scale landscapes to assess the motion behaviour and cognition of gastropods and bivalves.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences·2026
Same journal

Intertidal microcosms of wave-swept rocky shores: ecological and physiological insights from a uniquely stressful environment.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences·2026
Same journal

Temporal and spatial variation in temperature and oxygen at the microscale: key niche axes for aquatic life.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences·2026
Same journal

Natural microcosms in ecology: fulfilling the promise of model systems?

Philosophical transactions of the Royal Society of London. Series B, Biological sciences·2026
Same journal

Microbe-induced galls and plant defence: metabolite crosstalk in a co-evolutionary battle.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences·2026
See all related articles

Computational models show how brain cells form topographic maps, influencing dendritic field development and potentially explaining critical periods for vision development.

Area of Science:

  • Neuroscience
  • Computational Biology
  • Developmental Biology

Background:

  • Topographic map formation in the brain is crucial for sensory processing.
  • Axonal sprouting and retraction, driven by neurotrophic support competition, are key mechanisms.
  • Understanding dendritic morphology in cortical maps is essential for explaining visual system development.

Purpose of the Study:

  • To model the development of dendritic morphology in cortical maps using a computational framework.
  • To investigate the relationship between afferent segregation and dendritic bias in the primary visual cortex.
  • To explore the impact of visual stimulation patterns on critical periods and synaptic density.

Main Methods:

  • Developed a computational framework for topographic map formation based on axonal plasticity.

Related Experiment Videos

  • Modeled the development of ocular dominance columns in the primary visual cortex.
  • Simulated afferent segregation and dendritic field elaboration near column boundaries.

    • Main Results:

    • Cortical cells near column boundaries develop dendritic fields that avoid crossing functional input boundaries.
    • Afferent segregation was found to precede or occur simultaneously with dendritic bias.
    • Simulations suggest asynchronous optic nerve stimulation may extend the critical period for visual development.

    Conclusions:

    • The computational framework successfully accounts for aspects of dendritic morphology in cortical maps.
    • Dendritic bias may partially explain the critical period for monocular deprivation response.
    • Inter-ocular image correlations, influenced by factors like strabismic rearing, can affect synaptic innervation density.