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Related Experiment Videos

Burn wound infections: current status

B A Pruitt1, A T McManus, S H Kim

  • 1Department of Surgery, University of Texas Health Science Center at San Antonio 78229, USA.

World Journal of Surgery
|February 6, 1998
PubMed
Summary
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Burn wound infections are complex, influenced by patient and microbial factors. Early diagnosis via biopsy and histology is crucial for differentiating colonization from invasive infection, guiding effective treatment and improving patient survival.

Area of Science:

  • Infectious Diseases
  • Wound Care
  • Microbiology

Background:

  • Burn wounds are susceptible to opportunistic infections from endogenous and exogenous microorganisms.
  • Factors like burn severity, patient status, and microbial virulence influence infection risk.
  • Burn wound infections are classified by causative agent, invasion depth, and tissue response.

Purpose of the Study:

  • To review the pathophysiology and pathogenesis of burn wound infections.
  • To discuss diagnostic procedures and therapeutic strategies.
  • To highlight the importance of daily wound surveillance and histological examination for accurate diagnosis.

Main Methods:

  • Review of literature on burn wound infection pathophysiology, pathogenesis, diagnosis, and treatment.

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  • Emphasis on clinical and culture surveillance, biopsy, and histological examination.
  • Discussion of time-related changes in burn wound flora and resistance mechanisms.

    • Main Results:

    • Histological examination is the definitive method for distinguishing burn wound colonization from invasive infection.
    • Effective topical antimicrobial chemotherapy and early burn wound excision have reduced infection incidence.
    • Despite advances, invasive infections and post-healing complications like impetigo can still occur.

    Conclusions:

    • Accurate diagnosis through daily assessment and histological analysis is vital for appropriate management.
    • Prompt surgical removal of infected tissue is critical for bacterial and fungal infections.
    • Modern burn care has significantly decreased infection rates, mortality, and improved survival, though vigilance remains essential.