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Cytological changes in oral mucosa in denture stomatitis
J M Aguirre1, F Verdugo, J M Zamacona
1Departamento de Estomatologiá, Facultad de Medicina y Odontología, Universidad del País Vasco, Bilbao, Vizcaya, Spain.
Gerodontology
|July 1, 1996
Summary
Cytology reveals increased fungal cells and inflammatory markers in denture stomatitis (DS) patients compared to controls. This simple technique aids in managing inflamed oral mucosa associated with DS.
Area of Science:
- Oral pathology
- Microbiology
- Cytology
Background:
- Denture stomatitis (DS) is a common oral condition.
- Fungal infections, particularly Candida, are often implicated in DS.
- Cytological examination is a potential diagnostic tool.
Purpose of the Study:
- To compare cytological patterns in patients with atrophic and hyperplastic denture stomatitis versus controls.
- To assess the presence and significance of Candida in DS lesions.
- To evaluate the utility of cytology in managing denture stomatitis.
Main Methods:
- Cytological smears were analyzed from 94 patients with DS and 33 controls.
- Fungal cultures were performed on all participants.
- Smears were compared for cellular material, fungal cells, cell types, and inflammatory markers.
Main Results:
- Patients with DS showed higher amounts of cellular material, fungal cells, intermediate/parabasal cells, and polymorphonuclear leukocytes.
- Candida was present in 40% of DS patients and 30% of controls.
- Specific cytological changes for DS were not definitively identified, but inflammatory indicators were elevated.
Conclusions:
- Cytology is a useful, simple, and inexpensive method for assessing inflamed oral mucosa in denture stomatitis.
- The technique provides valuable information for the treatment and control of DS patients.
- Elevated fungal cells and inflammatory markers in DS suggest a role for cytology in patient management.