[Acrosyndrome in AIDS. Vascular toxicity of bleomycin revisited]

Several cases of vasculitis have been reported in AIDS patients. They may occur as idiopathic disease or result from infection or cryoglobulinemia. In patients with Kaposi's syndrome, treated with bleomycin. Raynaud's phenomenon or digital necrosis can occur. The vascular toxicity of bleomycin is well known and does not seem to be more frequent in AIDS patients compared with other patients treated with this drug. The relation between eumulative dose of bleomycin and occurrence of peripheral vascular disease is undear.