Related Experiment Video
Updated: Sep 30, 2026

Use of In Vivo Single-fiber Recording and Intact Dorsal Root Ganglion with Attached Sciatic Nerve to Examine the Mechanism of Conduction Failure
Published on: August 27, 2019
Collision technique. Physiologic block of nerve impulses in studies of motor nerve conduction velocity
Abstract:
Commonly encountered yet not widely appreciated sources of error in the study of motor nerve conduction velocities of the median and ulnar nerves include (1) spread of stimulating current to the nerve not under study, (2) recording a volume conducted potential from distant muscles, and (3) presence of anomalous crossover in the forearm between the median and ulnar nerves. Under these circumstances, it is desirable to block impulses in one nerve without affecting those in the other. This can be achieved simply by collision if a second stimulus is delivered distally to the nerve not being tested.
Related Concept Videos
Chemical Synapses
Because chemical synapses depend on the release of neurotransmitter molecules from synaptic vesicles to pass on their signal, there is an approximately one millisecond delay between when the axon potential reaches the presynaptic terminal and when the neurotransmitter leads to opening of postsynaptic ion channels. Additionally, this signaling is...
Neuromuscular Junction And Blockade
Local Anesthetics: Differential Sensitivity of Nerve Fibers
Chemical Synapses
Because chemical synapses depend on the release of neurotransmitter molecules from synaptic vesicles to pass on their signal, there is an approximately one millisecond delay between when the axon potential reaches the presynaptic terminal and when the neurotransmitter leads to opening of postsynaptic ion channels. Additionally, this signaling is...

