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[Pell-Nicol, a medicinal toothpaste]

I Popovici1, C Caraman, A Stefanache

  • 1Universitatea de Medicină şi Farmacie Gr. T. Popa, Iaşi.

Revista Medico-Chirurgicala a Societatii De Medici Si Naturalisti Din Iasi
|July 1, 1995
PubMed
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A new medicinal toothpaste, Pell-Nicole, formulated with sulfurous mud extract, demonstrates effective antimicrobial and anti-inflammatory properties. This natural toothpaste is recommended for various gum conditions and overall dental hygiene.

Area of Science:

  • Oral Health
  • Material Science
  • Pharmacology

Background:

  • Natural organic-mineral complexes, like sulfurous mud, offer potential therapeutic benefits.
  • Development of novel dental hygiene products is crucial for managing oral health issues.
  • Existing dental products may not fully address specific periodontal conditions.

Purpose of the Study:

  • To formulate and characterize a medicinal toothpaste using an atomized extract of Nicolina Iassy sulfurous mud.
  • To evaluate the physico-chemical properties and therapeutic effects of the novel toothpaste.
  • To assess the suitability of the toothpaste for treating gum affections and promoting dental hygiene.

Main Methods:

  • Formulation of a medicinal toothpaste incorporating an atomized sulfurous mud extract.

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  • Physico-chemical characterization including aspect, pH, abrasion value, and rheological properties.
  • Evaluation of therapeutic effects, specifically antimicrobial and anti-inflammatory actions.

    • Main Results:

    • The optimal toothpaste formula (Pell-Nicole) was identified with specific physical and chemical parameters.
    • Rheological measurements indicated plastic behavior with thixotropic character, ensuring stability and firmness.
    • Demonstrated significant antimicrobial and anti-inflammatory effects in preliminary testing.

    Conclusions:

    • The Pell-Nicole toothpaste, derived from natural sulfurous mud, exhibits favorable physico-chemical and therapeutic properties.
    • Its stability, firmness, and demonstrated efficacy make it a promising option for oral care.
    • Recommended for treating gum affections, periodontopathies, and maintaining general dental hygiene.